Ribonucleic acid interference induced gene knockdown
نویسندگان
چکیده
منابع مشابه
Cold-Induced Hypertension Ribonucleic Acid Interference Knockdown of Interleukin 6 Attenuates Cold-Induced Hypertension
The purpose of this study was to determine the role of the proinflammatory cytokine interleukin (IL) 6 in cold-induced hypertension. Four groups of male Sprague-Dawley rats were used (6 rats per group). After blood pressure was stabilized, 3 groups received intravenous delivery of adenoassociated virus carrying IL-6 small hairpin RNA (shRNA), adenoassociated virus carrying scrambled shRNA, and ...
متن کاملRibonucleic acid interference knockdown of interleukin 6 attenuates cold-induced hypertension.
The purpose of this study was to determine the role of the proinflammatory cytokine interleukin (IL) 6 in cold-induced hypertension. Four groups of male Sprague-Dawley rats were used (6 rats per group). After blood pressure was stabilized, 3 groups received intravenous delivery of adenoassociated virus carrying IL-6 small hairpin RNA (shRNA), adenoassociated virus carrying scrambled shRNA, and ...
متن کامل[Present and future of ribonucleic acid interference].
I would like to congratulate Dr. Pinazo-Durán et al.1 for the excellent editorial emphasizing a new phase in ophthalmology with a promising future, i.e., a highly active molecular biology field such as the genetic inhibition or interference with RNA (iRNA).2 The comments below are intended as a contribution to said editorial. The Human Genome Project was an international initiative which betwee...
متن کاملRibonucleic acid-induced changes in mammalian cells.
Previous experiments have shown that under proper conditions ribonucleic acid (RNA) can indeed initiate differentiation." 2 Of particular interest in this work is the development of highly specific structure. That the type of structure developed correlates with the tissue source of RNA indicates a response of the reacting tissue to a message carried directly by RNA or RNA-containing substances ...
متن کاملTransfer ribonucleic acid-induced hydrolysis of valyladenylate bound to isoleucyl ribonucleic acid synthetase.
When incubated with the appropriate substrates, purified Escherichia coli isoleucyl ribonucleic acid synthetase can form a complex with either isoleucylor valyladenylate which may be isolated by Sephadex filtration. Whereas the isoleucyladenylate complex reacts with transfer RNA (tRNA) to form isoleucyl-RNA, the valyladenylate complex breaks down in the presence of tRNA. In place of transacylat...
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ژورنال
عنوان ژورنال: Journal of Indian Society of Periodontology
سال: 2013
ISSN: 0972-124X
DOI: 10.4103/0972-124x.118309